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| Subject: Phenol,4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]- Synthesis Fri May 28, 2010 8:18 am | |
| In their published method, Elsinga et al. (8) synthesized [11C]verapamil by alkylation of desmethylverapamil with [11C]methyl iodide.Phenol,4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]-After high-performance liquid chromatographic separation, radiochemical yield was 16%, based on [11C]methyl iodide. Total synthesis time was 45 min, and radiochemical purity was >99%. The specific activity was >11.1 TBq/mmol (300 Ci/mmol) at end of synthesis (EOS).
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